{"id":16716,"date":"2015-01-02T15:05:45","date_gmt":"2015-01-02T14:05:45","guid":{"rendered":"http:\/\/narodnilijek.com\/web\/?p=16716"},"modified":"2018-03-13T21:05:52","modified_gmt":"2018-03-13T20:05:52","slug":"novi-eksperimentalni-lijek-za-rak","status":"publish","type":"post","link":"https:\/\/www.narodnilijek.com\/web\/novi-eksperimentalni-lijek-za-rak\/","title":{"rendered":"Novi eksperimentalni lijek za rak"},"content":{"rendered":"

\"noviNovi lijek koji je kod mi\u0161eva uni\u0161tio ljudske \u0107elije raka u trenutku dok su se dijelile, odnosno umno\u017eavale pokazao je dramati\u010dne rezultate u prvoj fazi istra\u017eivanja.<\/h2>\n

\u010cemu se nadaju istra\u017eiva\u010di<\/h2>\n

U laboratorijskim je uvjetima lijek OTS964 kod pet od \u0161est mi\u0161eva uni\u0161tio agresivne \u0107elije ljudskog raka plu\u0107a presa\u0111ene mi\u0161evima, uz malo nuspojava. Otkri\u0107e budi nadu u razvoj revolucionarnog lijeka koji bi bio u\u010dinkovit protiv raznih vrsta tumora, uklju\u010duju\u0107i rak dojke, mozga, jetre, mokra\u0107nog mjehura, kao i protiv nekih vrsta leukemije.<\/p>\n

>>\u00a0Kako nastaje rak<\/a><\/span><\/h2>\n

Testiranja lijeka OTS964 na ljudima mogla bi zapo\u010deti ve\u0107 ove godine. Lijek djeluje na jedinstveni na\u010din blokiraju\u0107i aktivnosti bjelan\u010devine TOPK koja je klju\u010dna za uspje\u0161nu diobu \u0107elija, a kod mnogih vrsta tumora proizvodi se u prevelikim koli\u010dinama.<\/p>\n

Smanjivanje toksi\u010dnosti lijeka<\/h2>\n

Ranija istra\u017eivanja pokazala su da lijek uspje\u0161no ubija tumorske \u0107elije, ali uz neprihvatljivu cijenu – ometao je stvaranje novih crvenih i bijelih krvnih zrnaca i naru\u0161avao imunolo\u0161ki sistem. U isto vrijeme pove\u0107avao je rizik stvaranja ugru\u0161aka pove\u0107anjem broja trombocita.<\/p>\n

>>\u00a05 faktora koji pove\u0107avaju rizik od raka dojke<\/a><\/span><\/h2>\n

Te su prepreke prevladane omatanjem lijeka u mikroskopske balone zvane liposome, \u0161to je smanjilo toksi\u010dnost lijeka za krv. Kod mi\u0161eva sa \u0107elijama ljudskog raka plu\u0107a taj se tumor uzgajao do veli\u010dine oko pola centimetra, a potom se lijek intravenski aplicirao dva puta sedmi\u010dno tokom tri sedmice.<\/p>\n

Tumori su nestali!<\/h2>\n
\n

Rezultat je bio brzo smanjivanje tumora, \u0161to je nastavljeno i nakon prestanka terapije. Rak je kompletno nestao kod pet od \u0161est mi\u0161eva bez vidljivih\u00a0nuspojava.<\/h3>\n<\/blockquote>\n

Velike doze lijeka davane su na usta drugoj skupini mi\u0161eva i kod svih \u0161est \u017eivotinja tumor je nestao, iako su nakon lije\u010denja imali niske vrijednosti bijelih krvnih zrnaca, oporavili su se u okviru dvije sedmice.<\/p>\n

Rezultati istra\u017eivanja objavljeni su u \u010dasopisu Science Translational Medicine. Mnogi lijekovi mogu zaustaviti rast, ali se rijetko vidi da tumor nestane.<\/p>\n","protected":false},"excerpt":{"rendered":"

Novi lijek koji je kod mi\u0161eva uni\u0161tio ljudske \u0107elije raka u trenutku dok su se dijelile, odnosno umno\u017eavale pokazao je dramati\u010dne rezultate u prvoj fazi istra\u017eivanja. \u010cemu se nadaju istra\u017eiva\u010di U laboratorijskim je uvjetima lijek OTS964 kod pet od \u0161est mi\u0161eva uni\u0161tio agresivne \u0107elije ljudskog raka plu\u0107a presa\u0111ene mi\u0161evima, uz malo nuspojava. Otkri\u0107e budi nadu […]<\/p>\n","protected":false},"author":1,"featured_media":16717,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"enabled":false},"version":2}},"categories":[3910,1],"tags":[82,3801,4477,773],"class_list":{"0":"post-16716","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-novosti","8":"category-zdravlje","9":"tag-lijek","10":"tag-lijek-za-rak","11":"tag-novi-lijek","12":"tag-rak"},"yoast_head":"\nNovi 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